By Inge Scharrer, Wolfgang Schramm
This publication includes the contribution to the thirty fifth Hemophilia Symposium, Hamburg 2004. the most subject matters are epidemiology, possibility of infections and inhibitors in hemophilia, continual hemophilic synovitis and long term result of orthopedic remedy, laboratory diagnostics and pediatric hemostaseology. the quantity is rounded off through a variety of unfastened papers and posters on hemophilia and hemorrhagic problems and inhibitors in hemophilia.
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Additional info for 35th Hemophilia Symposium Hamburg 2004: Epidemiology;Risk of Infections and Inhibitors in Hemophilia; Chronic lic Synovitis and Long-term Results of Orthopedic ... Hemostaseology;Free Lectures
Removal of TSE agents from blood products. Vox sang 2004; 87 Suppl 2: S7–S10 8. Gregori L, Mc Combie N, Palmer D, Birch P, Coker SOS, Giulivi A, Rohwer RG. Effectiveness of leukoreduction for removal of infectivity of transmissible spongiform encephalopathies from blood. Lancet 2004; 364: 529–531 9. Harrington T, Kuehnert MJ, Kamel H, Lanciotti RS, Hand S, Currier M, Chamberland ME, Petersen LR, Marfin AA. West Nile virus infection transmitted by blood transfusion. Transfusion 2003; 43: 1018–1022 10.
The principal conclusion was that »all patients with bleeding disorders … who have received clotting factor concentrates derived from UK-sourced plasma between 1998–2001 should be considered at risk of vCJD for public health purposes«. This has generated some alarm in the hemophilia community but also reflects an abrupt about-turn in opinion and policy at government level. The first case of BSE in cattle in the UK was identified in April 1985 . The initial official response was to try and contain the epidemic in cattle by culling of affected herds.
To block this route transfusion recipients are no longer allowed to donate blood in France, Update on the Safety of Clotting Factors, Mainly Regarding the risk of Transmission 27 England , Canada and Switzerland. According to the risk evaluation it remains to be decided whether a similar step is appropriate in Germany as well today. Much more desirable is the establishment of a sensitive test for the detection of the prion agent which would solve, as with other infectious agents, the majority of the problems we face today.
35th Hemophilia Symposium Hamburg 2004: Epidemiology;Risk of Infections and Inhibitors in Hemophilia; Chronic lic Synovitis and Long-term Results of Orthopedic ... Hemostaseology;Free Lectures by Inge Scharrer, Wolfgang Schramm